Acne Heat Treatment

Zeno is a simple electronic product designed to safely heat an acne lesion to a pre-set temperature range. This controlled and precise heating stimulates a heat-shock response in P. acnes, the bacteria causing at least 90% of all acne blemishes. The heat-shock response induces the bacteria to transcript a number of genes and activate heat shock proteins. These proteins cause the self-destruction of P. acnes within the lesion, reducing inflammation and allowing the skin to return to a healthy state.

Tyrell, Inc., the manufacturer of Zeno, uses its own ClearPoint™ Technology. with heat shock response to destroy P. acnes.

ClearPoint™ Technology

ClearPoint™ technology is the key to Tyrell, Inc.’s ability to provide heat therapy for the successful treatment of skin lesions.
 
Tyrell's proprietary ClearPoint™ technology delivers a precisely controlled heat dose for a specific period of time to a pimple. This heat triggers a cascade of events that include the induction of heat shock protein responses and the subsequent killing of the bacteria. This effectively reduces the inflammatory response and allows the skin to return to a healthy state more quickly.

The Science Behind ClearPoint™ Heat Shock Response

Tyrell performed numerous lab studies on P. acnes to assess the temperature range in which heat shock response occurs in this bacteria, including a water bath and a thermal cycler study, known for accuracy to tenths of a degree. DNAtrix, Inc., a molecular pharmaceutical company jointly owned by Dr. Conrad and the Board of Regents of the University of Texas , performed the thermal cycler testing which was critical in determining if P. acnes' heat shock response occurs below the point of heat damage of human skin. Furthermore, these tests were critical in assessing the rate of P. acnes death at various temperatures over time (temperature versus time). The results indicated significant death of P. acnes at a temperature well below the thermic damage of human skin.

Warnings

• Use Zeno only for pimples.
• Do not use Zeno for skin lesions such as moles, warts or ingrown hairs.
• Do not use Zeno for insect or spider bites or stings.
• Do not use Zeno for skin infections or for open sores or wounds because it may delay proper treatment or injure your skin.
• Do not use Zeno if your skin is sensitive to heat, sun or chemicals because Zeno uses heat to treat pimples and the heat may damage your skin.
• Zeno will not work when used on blemishes such as blackheads or whiteheads.
• Zeno should not be used by persons with severe nodular or cystic acne.
• CONTACT your health care professional and stop using Zeno if you have an adverse reaction from using Zeno. If you do not get medical advice your reaction may get worse.
• Patients included in our clinical trials experienced little reaction to the low-level heat. Other than some temporary skin redness following a treatment cycle, no other adverse side effects were reported.
• Zeno does not replace good skin hygiene so don't abandon your regular skin care routine. It simply takes over when pimples overwhelm your skin's natural balance.
• Zeno’s Wall Charging Plug is designed for use with no more than 120v at 60 cycles only. Do not use with any other electrical service as this will VOID the warranty.