According to a 2005 study in the American Journal of Clinical Dermatology, DMAE facial gel applied daily for 16 weeks was shown to be safe and effective in the reduction of forehead lines and crows feet, and improved lip shape and fullness and the overall appearance of aging skin.

These effects did not subside during a 2-week pause in the product's use. Reductions were noted in the appearance of coarse wrinkles, under-eye dark circles, nasolabial folds, sagging neck skin, and neck firmness. The benefits of DMAE in dermatology include a potential anti-inflammatory effect and a documented increase in skin firmness with possible improvement in underlying facial muscle tone.

Used in combination with the Wrinkle Wand, this product will help accelerate the effectiveness of the Wrinkle Wand and yield compounded results.